Flow synthesis monitoring

On-line, direct monitoring of flow chemistry systems using the expression CMS allows chemists to get real time information on starter chemicals, impurities and final compound.
  • Real Time Information
  • Optimize conditions
  • Monitor reaction yield

A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis
D.E. Fitzpatrick, C. Battilocchio, S.V. Ley
Org. Process Res. Dev., Article ASAP
DOI: 10.1021/acs.oprd.5b00313

Online Quantitative Mass Spectrometry for the Rapid Adaptive Optimisation of Automated Flow Reactors
N. Holmes, G.R. Akien, R.J.D. Savage, C. Stanetty, I.R. Baxendale, A.J. Blacker, B.A. Taylor, R.L. Woodward, R.E. Meadows, and R.A. Bourne
React. Chem. Eng., 2016, Advance Article DOI: 10.1039/C5RE00083AD