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Chip-Based Infusion (Mode 1)

High voltage is applied to pipette tip. Nanoelectrospray ionization is initiated. Ions spray into mass spectrometer.

The TriVersa NanoMate system operating in Chip-Based Infusion mode (Mode 1) utilizes the ESI Chip™ - a silicon-based integrated nanoelectrospray microchip device developed using deep reactive ion etching technologies.  The ESI Chip consists of an array of 400 nanoelectrospray emitters with different inner diameters allowing for flow rates of 20 to 300 nL/min.  The manufacturing process for the ESI Chip allows for consistent nozzles providing a robust and reliable platform.  The nozzles on the ESI Chip provide a long, stable spray, and in infusion mode, eliminate sample-to-sample carryover.

Typical applications in this mode include:

Protein Identification

Noncovalent Interactions

Lipids Analysis

How it works >>

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