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Our system enables greater than 10 times more sensitivity than LC/MS/MS for protein biomarker discovery, identification, and metabolomics studies.
- Integrated system to perform LC/MS coupling, fraction collection,
and chip-based infusion to identify and to characterize trace level-biomarkers
- Rapidly switch between mass spectrometry platforms to obtain positive
ion, precursor ion, neutral loss scanning, or MSn analysis as well as
accurate mass
- Improved signal-to-noise with the power of signal averaging and the
ability to optimize collision energy
- Accelerate biomarker discovery by creating more time across complex
LC peaks
Learn More about this application
by viewing the following web presentation
Proteomics
with Dr. Jennifer Sutton
"NanoMate-ESI-MS (Advion BioSciences) coupling works well for metabolic
fingerprinting providing patterns recognition. Fast, reproducible, and automated
nano-ESI infusion is suitable for rapid and comprehensive analysis of large
sample sets."-- Vladimir Tolstikov, UC Davis, Fiehn
Lab
How it works >>
Following are peer reviewed articles, application notes, and posters demonstrating Advion's technology. You will need to sign in to access the documents listed below.
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Product Notes
Articles:
- "Controlled Protein Precipitation in Combination with Chip-based Nanospray Infusion Mass Spectrometry. An Approach for Metabolomics Profiling of Plasma;" K.O. Boernsen, et al.; Analytical Chemistry; 11-3-2005
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- "Dynamic Range and Mass Accuracy of Wide-Scan Direct Infusion Nanoelectrospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry-Based Metabolomics Increased by the Spectral Stitching Method;" M.R. Viant et al Anal. Chem. 2007, 79, 4595-4602
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Scientific Posters
- Simultaneous Collection of On-line LC-MS/MS and LC Fractions with Post-Column Splitting: Maximizing MS Infomation of Complex Samples with Nanoelectrospray Ionization - G. Schultz et al. - Advion
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