Biomarker Analysis

Biomarker analysis

The TriVersa NanoMate enables greater than 10 times more sensitivity than LC/MS/MS for protein biomarker analysis, identification, and metabolomics studies.

  • Rapidly switch between mass spectrometry platforms to obtain positive ion, precursor ion, neutral loss scanning, or MSn analysis as well as accurate mass
  • Improved signal-to-noise with the power of signal averaging and the ability to optimize collision energy
  • Accelerate biomarker analysis by creating more time across complex LC peaks

"NanoMate-ESI-MS (Advion BioSciences) coupling works well for metabolic fingerprinting providing patterns recognition. Fast, reproducible, and automated nano-ESI infusion is suitable for rapid and comprehensive analysis of large sample sets."-- Vladimir Tolstikov, UC Davis, Fiehn Lab

How LC/MS fraction collection works for protein biomarker analysis »

Following are peer reviewed articles, application notes, and posters demonstrating Advion's technology. You will need to sign in to access the documents listed below. You must register before you sign in for the first time.

Product Notes

Articles:

  • "Controlled Protein Precipitation in Combination with Chip-based Nanospray Infusion Mass Spectrometry. An Approach for Metabolomics Profiling of Plasma;" K.O. Boernsen, et al.; Analytical Chemistry; 11-3-2005
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  • "Dynamic Range and Mass Accuracy of Wide-Scan Direct Infusion Nanoelectrospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry-Based Metabolomics Increased by the Spectral Stitching Method;" M.R. Viant et al Anal. Chem. 2007, 79, 4595-4602
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Scientific Posters

  • Simultaneous Collection of On-line LC-MS/MS and LC Fractions with Post-Column Splitting: Maximizing MS Infomation of Complex Samples with Nanoelectrospray Ionization - G. Schultz et al. - Advion
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Lipidome Profiling of Colon Adenocarcinoma Cell lines