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| LC/MS is performed while simultaneously collecting fractions in 96/384 well plate. |
In liquid chromatography/mass spectrometry (LC/MS) fraction collection mode, the TriVersa NanoMate allows users to couple any conventional HPLC system to the TriVersa NanoMate for MS analysis. The effluent is split post column with a portion directed to a conventional LC/MS interface while the remainder of the split effluent is directed to collect at time segments into a multi-well plate. The chromatogram is thereby “cataloged” for future analysis. Following LC/MS, the researcher is able to select fractions of interest for more in-depth analysis via MS/MS. The process gives researchers the ability to spend more time analyzing complex portions of their samples without having to reinject. LC/MS with simultaneous fraction collection is ideally suited for researchers interested in metabolite identification, biomarker discovery, and protein characterization or any application that requires more time for analysis than what is allowed during conventional LC/MS.
Typical applications in this mode include:
Metabolite Identification
Protein Biomarker Discovery
QA/QC Antibodies
Post-Translational Modifications
Top-Down Proteomics
How it works >> |
