Advion BioSystems, Agilent Technologies Announce Co-Marketing Agreement for Advion’s TriVersa NanoMate Chip-Based Nanoelectrospray System with Agilent’s Mass Spectrometers

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ITHACA, NY, and SANTA CLARA, Calif., November 12, 2008 — Advion BioSystems, Inc. and Agilent Technologies Inc. (NYSE: A) jointly announced today that they have signed a non-exclusive co-marketing agreement to co-promote the Advion TriVersa NanoMate system with Agilent mass spectrometers. The TriVersa NanoMate is an automated fraction collection and nanoelectrospray system that connects to the inlet of a mass spectrometer. It combines the benefits of micro or capillary-scale liquid chromatography (LC), with simultaneous fraction collection and subsequent chip-based infusion of the LC fractions in one system to increase the performance and automation of a mass spectrometer.

The TriVersa NanoMate differs from Agilent’s 1200 Series HPLC-Chips in that the former operates at capillary and micro flow rates needed for fraction collection, enabling collection of individual peaks for highly sensitive infusion MS analysis. The latter provides on-line LC/MS at nanoflow rates that are well-suited to applications where the amount of sample available is limited.

Agilent and Advion have co-developed a bracket to interface the TriVersa NanoMate to Agilent mass spectrometers to provide life science users with the power of automated sample infusion on the Agilent family of LC/MS systems.

Under the agreement, the companies will co-market the TriVersa NanoMate and Agilent mass spectrometer systems with each company responsible for its individual products. Agilent will sell and support its mass spectrometers and Advion will sell and support the TriVersa NanoMate and the bracket to interface the TriVersa NanoMate to Agilent mass spectrometers. Each company will co-promote their products at industry tradeshows and conferences.

“The combination of the TriVersa NanoMate with Agilent mass spectrometers provides a powerful tool for life science researchers,” said Jack Henion , Advion’s Chief Scientific Officer. “In particular, the efficiency and sensitivity of direct infusion of LC fractions with the TriVersa NanoMate and the new Agilent 6530 Accurate-Mass Q-TOF instrument provides researchers with exceptional sensitivity and speed for proteomics, metabolism, lipidomics, and biomarker applications.”

Ken Miller, Global Sr. Marketing Manager for Mass Spectrometry at Agilent, added, “ The Advion TriVersa Chip-based system will be very complementary to the Agilent nanoflow HPLC-Chip technology. The TriVersa system offers some added capabilities such as fraction collection of peaks of interest and should prove to be very useful for protein characterization and biomarker discovery experiments. Many of our customers have asked for the integration of the Advion system with our 6000 Series LC/MS products, especially the Agilent 6500 Accurate Mass Q-TOF LC/MS system.”

Agilent manufactures and markets life science and chemical analysis solutions and is a worldwide leader in mass spectrometry, with powerful, reliable LC/MS solutions for applications as diverse as discovery of cancer biomarkers and quantification of pesticides in food and water. Advion provides innovative microfluidic systems for mass spectrometry (MS) and nuclear medicine applications.

About Agilent Technologies
Agilent Technologies Inc. (NYSE: A) is the world’s premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. The company’s 20,000 employees serve customers in more than 110 countries. Agilent had net revenue of $5.4 billion in fiscal year 2007. Information about Agilent is available on the Web at

About Advion BioSystems, Inc.
Advion is the scientific leader in microfluidic systems. The company’s scientific knowledge base creates unique nanotechnologies delivering speed, flexibility, and exceptional data quality. Advion is the microfluidics supplier of choice for customers demanding scientific excellence, more information from complex samples, and greater throughput. More about the company can be found at

For Advion:
Heather Scollins
Sr. Marketing Communication Specialist
Advion BioSciences, Inc.
p: 1.607.266.0665 ext. 333