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 In this application note, a simple, cost-effective UHPLC/UV method is presented for the quantitation of cannabinoids using an Advion Interchim Scientific AVANT™ UHPLC system. With simple sample preparation, requiring only dilution, the method can be used for the analysis of plant material, oils, distillates and isolates.

Recorded June 15, 2022. Join Christopher Thomson, Researcher at Heriot-Watt University, as he shares his work expanding the tool kit of automated flow synthesis with the development of in-line flash chromatography purification. In this webinar, you will learn: An introduction to flow chemistry and in-line purification technologies. An overview of prior continuous chromatography methods, their …

 In this application note, we describe a novel method to perform the continuous isolation of flow synthesis products from residual starting materials, catalysts or by-products to expedite chemical discovery. A promising new approach is highlighted here, featuring the Advion Interchim Scientific puriFlash® 5.250 preparative LC system. The first results of our cooperation with the VilelaLAB …

Xianlin Han, Kui Yang and Richard W. Gross Abstract Lipidomics, defined as the large-scale study of the pathways and networks of cellular lipids in biological systems, is an emerging and rapidly expanding research field. Although lipidomics has only emerged as a distinct field within the past few years, numerous new discoveries and advances have already …

Helium shortages are not new – annually, scientists see the cost of helium rise and fall like the stock market. Except this isn’t just a financial impact. Global helium shortages threaten to derail research and essential industry functions, taking down GC and high-field NMR instruments, bringing a once state-of-the-art lab down to a bare-bones facility. …

Avoid workflow bottlenecks by streamlining the flash purification process in your lab. This whitepaper can help you identify, reduce, or even eliminate these bottlenecks, tanking your standard operational time from hours to minutes. Learn how essential tools including TLC, a smartphone application and a simple dipping probe for fraction ID offer a novel, systematic approach …

The NEW puriFlash® XS-Vap, your intuitive laboratory evaporator. X-tra compact. X-tra intuitive. X-tra efficient. X-tra evaporation. Reduce evaporation time and gas consumption with the most advanced evaporator on the market. The puriFlash® XS-Vap offers an extensive range of benefits over the competition: Compact and robust Dedicated to solvent evaporation & concentration Up to 90 samples in parallel …

In this application note, we used the Advion Interchim Scientific puriFlash® 5.250 to purify five active ingredients found in over-the-counter (OTC) and prescription drugs including caffeine, glafenine, ketoprofen, flavone, and fenofibrate, by a preparative purification workflow. The compounds were then confirmed using the expression® compact mass spectrometer.

Cocaine is a globally used illicit drug and its widespread use remains a significant public health concern. It is known that US paper currency in general circulation is contaminated with cocaine. There are several possible explanations for this: contamination due to handling during drug deals, the use of rolled up bills for snorting or inhalation, …

Cannabis and hemp products are becoming much more available for medicinal and recreational use making routine testing for toxic heavy metals much more important. Advion introduces the SOLATION® ICP-MS for the analysis of heavy metals in cannabis plant and cannabis product samples. While there are no federal guidelines for heavy metals in cannabis, states where …

The compound synthesis, purification, and confirmation processes often present challenges. From ensuring successful synthesis of your product, setting up a flash purification method, and finally confirming ID of fractions, the lengthy workflow can be time consuming and repetitive. This webinar will provide a foundation for flash purification processes and will showcase a novel workflow concept …

Flash chromatography has traditionally used UV absorption as the main method of detection for compounds during a purification process. While UV absorption is broadly applicable to many classes of compounds, it has limited specificity to individual compounds in a mixture and misses classes of compounds that do not carry chromophores. Mass-directed fraction collection gives users the ability to collect …

Benjamin T. Manard*, Kayron T. Rogers, Brian W. Ticknor, Shalina C. Metzger, N. Alex Zirakparvar, Benjamin D. Roach, Debra A. Bostick, and Cole R. Hexel Abstract The ability to directly measure uranium isotope ratios on environmental swipes has been achieved through a solution-based microextraction process and represents a significant advancement toward the development of a …

Lab Manager Tech Trends Webinar. Recorded August 11, 2021. This webinar features the Interchim PuriFlash® flash purification and preparative HPLC system and demonstrates separation of natural products, purification of specific target molecules and the combination of mass spectrometry detection of the same both for product confirmation and mass directed fraction collection using an Advion expression® …

Authors: Regensburg University Hospital, European Molecular Biology Laboratory, Germany; University of Southern Denmark, Denmark Abstract Lipidomics data require consideration of ions with near-identical masses, which comprises among others the Type-II isotopic overlap. This overlap occurs in series of lipid species differing only by number of double bonds (DBs) mainly because of the natural abundance of …

In this exclusive webinar, our cannabis instrumentation experts will share information about solutions that relieve the purification bottleneck for processors. This 15-minute on-demand session will cover: Pesticide remediation and dewaxing THC remediation Minor cannabinoid purification In-house analytical System and Consumable options

This 159-page educational eBook is a comprehensive manual on high-throughput purification – from the theory and principles of chromatography through to method development and column selection. This valuable book offers an incredible opportunity for both beginners and experts alike to learn more about the science of chromatography and can improve your workflow and productivity. Chapter …

Authors: University of Graz, BioTechMed-Graz, Austria; Max Planck Institute of Molecular Cell Biology and Genetics, Germany Abstract Triacylglycerol (TG) and steryl ester (SE) lipid storage is a universal strategy to maintain organismal energy and membrane homeostasis. Cycles of building and mobilizing storage fat are fundamental in (re)distributing lipid substrates between tissues or to progress ontogenetic …

This webinar features several useful tools to simplify or even eliminate the sample preparation involved prior to mass spectrometry. In this educational session you will learn about several prep-free mass spec techniques that are available, and how to select which method is best for your analysis. Advion will share their perspectives on some of the …