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The discovery of chemical reactions is an inherently unpredictable and time-consuming process. An attractive alternative is to predict reactivity, although relevant approaches, such as computer-aided reaction design, are still in their infancy. Reaction prediction based on high-level quantum chemical methods is complex, even for simple molecules. Although machine learning is powerful for data analysis, its …

In this application note, the inert atmospheric solid analysis probe (iASAP) and expression Compact Mass Spectrometer (CMS) was used to quickly sample and measure a modification of a published synthesis by Pfeiffer. The research in this application note was presented at the 66th Annual Conference of the American Society of Mass Spectrometry (ASMS 2018)

 In this application note, the Advion expression Compact Mass Spectrometer (CMS) coupled with the Advion AVANT UHPLC (LC/CMS) was used to measure the concentration of cannabinoids from commercially available CBD oils for a comparative test against the product labels.  The research in this application note was published in Cannabis Science & Technology Magazine May/June 2019 …

Introducing a new way to analyze and present mass spectral data, the Advion Peak Express patented software uses the delta spectrum (∆S) to quickly and automatically detect significant peaks within mass spectra based on their relative change in intensity over time instead of their absolute intensity. Find impurities and minor components that would otherwise be …

This webinar examines three different workflows surrounding compact mass spectrometry as they apply to cannabis law enforcement, it’s natural product research, and product control.

In this webinar, Advion’s Scientific Founder, Jack Henion, Ph.D., will discuss his research using a direct analysis probe coupled with the expression CMS to analyze chemical compounds in Cannabis. During this webinar you will learn more about: A simple, sensitive and selective ASAP sample introduction approach to measure the presence and relative quantitative composition of …

Thanks to the diminishing size and cost of mass spectrometers, coupled with their increasing robustness and ease of use, universities are now starting to furnish their undergraduate chemistry laboratories with this advanced analytic tool. “My favorite learning environment is the laboratory,” explains Paul A. Flowers, professor of analytical chemistry at University of North Carolina at …

The expression CMS provides essential information quickly and improves the chemist’s workflow by using a direct analysis probe, otherwise known as ASAP® (Atomospheric Solids Analysis Probe) permits chemists affordable and reliable sample analysis of solid and liquid samples such as reaction mixtures, food samples, natural products and tablets. Chemists simply dip the closed end of …

The Atmospheric Solids Analysis Probe (ASAP™) allows chemists to directly analyze liquid and solid samples by mass spectrometer without the need for sample preparation. The inert ASAP (iASAP) is a modification of this technique, allowing easy sampling of air-sensitive compounds, such as metal catalysts and organometallics, from reactions that are carried out in a glove …

Volatile Atmospheric Pressure Chemical Ionization (vAPCI) combined with Advion’s expression® compact mass spectrometer (CMS) is a fast and easy method to analyze the headspace of a sample with no additional sample prep. The vAPCI ion source is a simple, powerful tool for gas phase sample analysis. The technique can quickly and confidently identify compounds in …

Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. The video demonstrates analysis of a reaction mixture. Watched the video and ready to learn more? View More Touch Express Details

Advion’s Plate Express is ideal for fast, easy TLC/MS analysis. Coupled with the expression compact mass spectrometer, the TLC plate reader allows prep-free sampling and data in less than 30 seconds.

Advion’s direct atmospheric solids analysis probe, otherwise known as ASAP, permits chemists fast and reliable sample analysis of liquid and solid samples such as reaction mixtures, food samples, natural products and tablets.

Advion’s expression CMS paired with the Atmospheric Solids Analysis Probe (ASAP) can quickly and easily be used to screen an unidentified drug mixture in this mobile field testing dramatization.

We demonstrate a cost-effective UHPLC/CMS method for the analysis of chloramphenicol in milk with a detailed discussion of sensitivity, linear response range, carryover and robustness using the Advion expression Compact Mass Spectrometer (CMS) and Advion AVANT UHPLC System. This application note was adapted from a poster that was presented at the 2019 ASMS Conference on …

Using separation from the AVANT UHPLC system coupled to the expression Compact Mass Spectrometer (CMS), cannabinoids from commercially available CBD oils are measured for concentration against product label claims for a comparative test. This poster was presented at the 2019 Cannabis Science Conference East in Baltimore, MD.

We demonstrate a cost-effective UHPLC/CMS method for the analysis of chloramphenicol in milk with a detailed discussion of sensitivity, linear response range, carryover and robustness using the Advion expression Compact Mass Spectrometer (CMS) and Advion AVANT UHPLC System. This poster was presented at the 2019 ASMS Conference on Mass Spectrometry and Allied Topics in Atlanta, …