Advion Launches Novel Metal Catalyst Reaction Monitoring Probe Collaborates with Albert-Ludwigs-University of Freiburg and Files Related Patents

Dedicated to Science, Dedicated to You

March 13, 2016 – Ithaca, NY – Advion, Inc., a leading systems and consumables developer for the life sciences industry, announced during this week’s 251st American Chemical Society National Meeting & Exposition in San Diego, California the introduction of a breakthrough sample introduction technique for its line of expression compact mass spectrometers (CMS). The new iASAP (inert Atmospheric Solids Analysis Probe (ASAP®)) was originally developed at the University of Pennsylvania by Charles McEwen, Ph.D, and enhanced by the Freiberg researchers.

ASAP gives chemists and chemistry students the ability to ionize liquid and solid samples for analysis by mass spectrometer without the need for sample preparation. The technique allows a synthetic chemist to perform real-time reaction monitoring by simply dipping the ASAP probe into their reaction mixture and inserting the probe into the atmospheric pressure chemical ionization (APCI) source of the CMS. Mass spectral data is presented within seconds.

For air-sensitive compounds, such as metal catalysts, iASAP is a viable technique to prevent oxidization and facilitate their assay. Advion credits Professor Ingo Krossing’s group at the Albert-Ludwigs-University of Freiburg (Freiberg) with modifying the ASAP probe to protect the compounds in inert gas as they are transferred to the CMS, enabling such measurements without the traditonal need for glove boxes. Advion and Freiburg negotiated a transfer of the patent estate to Advion to allow global commercialization.

“The best product enhancements come from our users,” says Simon Prosser, Vice President of Marketing. “A large percentage of all synthetic chemistry involves air-sensitive compounds and needs to be carried out in glove boxes or Schlenk lines and Advion is pleased to have collaborated with Prof. Krossing’s group to bring this enhancement to others.”

The iASAP is available for quoting and will begin shipping in May 2016.