Advion's TriVersa NanoMate System Essential in Melamine Analysis

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March 31, 2007 — ITHACA, N.Y., March 31, 2007 As previously reported, Advion BioSciences, innovators in products for the life science industry, was called upon to collaborate with Cornell’s College of Veterinary Medicine, the FDA and other laboratories across the country to assist in analyzing samples associated with the recent pet food recall.

Following reports in the national news of a chemical named aminopterin being present in the gluten material used in components of the pet food, Advion sought to confirm the presence of aminopterin as well as identify any other foreign substances that may be present in the gluten materials. Advions efforts were directed by Dr. Jack Henion, Chief Scientific Officer. Advion’s BioServices division is a well-respected bioanalytical laboratory serving the pharmaceutical industry. Scientists from the bioanalytical laboratory worked closely with the TriVersa NanoMate application scientists to analyze the samples using LC/MS/MS.

Advion’s TriVersa Nanomate readily confirmed aminopterin in positive control standards at low part per million levels, but detected no evidence for aminopterin in any of the gluten samples reportedly associated with the pet food poisonings. During the course of these experiments, the FDA reported the presence of another chemical in the gluten called melamine. The TriVersa NanoMate system readily detected and confirmed this chemical. More information regarding this Advion product can be found at

About Advion:
Founded in 1993, and known as a leader in the industry, Advion BioSciences, Inc. are pioneers in bioanalytical services and innovators of products for the life science industry.

For Advion:
Amy Boardman
Manager of Corporate Marketing Communications
607.266.9162 ext. 314