Application Note

Analysis of Iohexol using the Advion Interchim Scientific® AVANT® HPLC and expression® CMS System

 
Analysis of Iohexol using the Advion Interchim Scientific<sup>®</sup> AVANT<sup>®</sup> HPLC and ex<u>press<strong>ion</strong></u><sup>®</sup> CMS System

Iohexol is a widely used non-ionic imaging agent that improves contrast for x–ray analysis. Its low osmolality allows for a rapid clearance via the kidney, preventing reabsorption and further metabolization. This makes iohexol a compound with a better safety profile compared to other imaging agents.

In this application note, a simple and accurate HPLC-CMS method for iohexol analysis is introduced.