Application Note
Qualitative Analysis of Oligonucleotides Using The Advion Interchim Scientific® HPLC-UV/MS System
![Qualitative Analysis of Oligonucleotides Using The Advion Interchim Scientific<sup>®</sup> HPLC-UV/MS System](https://www.advion.com/wp-content/uploads/Screenshot-2023-09-22-at-9.39.05-AM.png)
Oligonucleotides have gained significant attention in biopharmaceutical development due to their ability to modulate gene or protein expression. This application note aims to demonstrate the HPLC/UV analysis of multiple oligo samples and utilize HPLC/CMS analysis to determine their molecular weight.