Rapid and Automated Peptide Mapping of Protein Therapeutics

In this application note, we present a high-throughput, automated strategy for protein and antibody characterization that addresses the need for precise, reliable analysis of therapeutic proteins. Using enzymatic digestion in 96-well plates and rapid, chromatography-free injection into high-resolution mass spectrometers, this workflow enables full sequence characterization with throughput of up to 1,000 mAbs per day.