Application Note

Suzuki Reaction Monitoring Using Compact Mass Spectrometry with TLC Interface

 
Suzuki Reaction Monitoring Using Compact Mass Spectrometry with TLC Interface

This application note presents an online thin-layer chromatography (TLC)/CMS technique using the Advion expression compact mass spectrometer (CMS) and Plate Express™ interface to provide compound structural information without sample preparation after TLC separation. A Suzuki reaction for the synthesis of 4-aminobiphenyl will be demonstrated. The online TLC/CMS technique provides rapid and accurate determination of reaction mixture components without the need for off-line TLC sample preparation procedures.

Advion respects your privacy. We will not give your email address to third parties or send you unwanted email.