Application Note

The Preparation, Confirmation, and Quantitation of the Ionic Imaging Contrast Agent, Gd(III)-DOTA

 
The Preparation, Confirmation, and Quantitation of the Ionic Imaging Contrast Agent, Gd(III)-DOTA

In this application note, we demonstrate a complete solution for the synthesis, purification, and quantitation of Gd(III)-DOTA, an ionic imaging contrast agent with better chemical stability and lower toxicity compared to the currently used Gd-(DTPA).