Application Note
The Preparation, Confirmation, and Quantitation of the Ionic Imaging Contrast Agent, Gd(III)-DOTA
![The Preparation, Confirmation, and Quantitation of the Ionic Imaging Contrast Agent, Gd(III)-DOTA](https://www.advion.com/wp-content/uploads/Screenshot-2023-03-22-at-11.40.36-AM-2.png)
In this application note, we demonstrate a complete solution for the synthesis, purification, and quantitation of Gd(III)-DOTA, an ionic imaging contrast agent with better chemical stability and lower toxicity compared to the currently used Gd-(DTPA).