The new edition of our “Analytical Sciences, Synthesis & Purification” catalog is available now! Offering a full suite of innovative products and technologies from Advion Interchim Scientific, this catalog features over 20,000 products ranging from consumables and reagents to instrumentation.
Not only a product resource, the catalog features in-depth scientific information to improve your daily workflow, including sample preparation tips and tricks, analysis technologies such as GC and LC/MS, and help selecting the best consumables for your workflow or purification.
Take advantage of this extensive guide to boost your lab with:
Mass spectrometry is an analytical technique used to determine the mass-to-charge ratio of ions in a sample and therefore the sample composition. This method is used across many industries including food and beverage, environmental monitoring, and clinical. There are many features of mass spectrometers that must be considered before purchasing such as the required mass analyzer technology, ionization source, and dissociation technique. Join Lab Manager and our panel of experts as we discuss how to decipher mass spectrometry technology offerings and find the right solution for your lab.
As an attendee, you will learn more about:
Available technology for performing mass spectrometry
Features to consider when purchasing mass spectrometry instruments
How to find the right mass spectrometer for your application
Dr. Jack Henion presents the possibility of using the Advion Interchim Scientific expression® Compact Mass Spectrometer (CMS) for ‘roadside breath testing’ of THC DRUID (driving under the influence of drugs) with the use of a small plastic breath collection device from Breath Explor of Uppsala, Sweden. This device serves as a simple, acceptable collection device for individuals in contrast to venous puncture with a needle or other means of collecting a biological sample.
In this ASMS 2020 Reboot presentation, you will learn:
Breath sample collection with the Breath Explor device
The potential benefits and challenges of a roadside LC/CMS testing system including an automated robot for sample preparation with the Advion Interchim Scientific expression® CMS and Advion Interchim Scientific AVANT UHPLC
The Advion LC/CMS system provides accurate and sensitive results when used to analyze breath samples for THC
Authors: Olof Beck2, Jack Henion1, Sabina Seferaj2, Peter Stamback3 1Advion, Inc., Ithaca, NY 2Karolinska Institute, Stockholm, Sweden 3Breath Explore, Munkplast AB, Uppsala, Sweden
In this application note, the Advion Interchim Scientific expression® Compact Mass Spectrometer (CMS) with volatile APCI (vAPCI) is used to analyze volatile compounds present during the fermentation of homebrewed beer by Stephanie Rankin Turner of Loughborough University.
The complex flavor of beer is primarily a result of the ingredients used, the brewing method, and conditions during fermentation. The analysis of beer throughout this process can be invaluable. Being one of the most widely consumed beverages worldwide, rapid and reliable analytical techniques are essential to keep up with demand and production.
This note demonstrates the use of the Advion Interchim Scientific expression® CMS with vAPCI for the analysis of volatile compounds from the headspace of homebrew beer and hops. The Venturi-assisted interface of the instrument enabled rapid sampling of volatiles, allowing the changing volatile profile of the homebrew to be observed throughout the fermentation process. This simple method would be suitable for fast quality control during alcoholic beverage production.
Metal-based compounds have found utility in various fields such as clinical, energy, food safety and environmental to name a few. Creating the metal complex is the last step in a synthetic process, but it is critical to have the proper conditions for monitoring air-sensitive compounds to get the desire product and that side products are kept to a minimum to maximize yield.
In this application note, the inert atmospheric solid analysis probe (iASAP) and expression Compact Mass Spectrometer (CMS) was used to quickly sample and measure a modification of a published synthesis by Pfeiffer.
The research in this application note was presented at the 66th Annual Conference of the American Society of Mass Spectrometry (ASMS 2018)
For Direct Mass Analysis of Air-Sensitive Samples, Catalysts and Organometallics at the Bench With the expression® CMS
The Atmospheric Solids Analysis Probe (ASAP®) allows chemists to directly analyze liquid and solid samples by mass spectrometer without the need for sample preparation at the bench, right next to the reaction. The inert ASAP (iASAP) is a modification of this technique, allowing easy sampling of air-sensitive compounds, such as metal catalysts and organometallics, from reactions that are carried out in a glove box or Schlenk line to prevent oxidation.
The technique allows a synthetic chemist to perform real-time reaction monitoring by sampling the compound with the special iASAP probe, which is designed to provide access to a sample protected in a glovebox or Schlenk line, then transferring the sample to the CMS, while continuing to protect it in an inert environment where it is ionized by atmospheric pressure chemical ionization (APCI). Mass Spectra are acquired in seconds.
Metal based compounds have found utility in various fields such as clinical, energy, food safety and environmental to name a few. Creating the metal complex is the last step in a synthetic process when ligands are bound to the metal center. Once made, these metal complexes can be used anywhere from stereospecific synthesis to anti-cancer drugs. It is critical that reaction conditions are providing the desired product and that side products are kept to a minimum to maximize yield. Presented here is the use of an inert atmospheric solid analysis (iASAP) probe to quickly sample and measure the reaction via mass spectrometry.
P. Perez-Hurtado, E. Palmer, T. Owen, C. Aldcroft, M.H. Allen, J. Jones,,C.S. Creaser, M.R. Lindley, M.A. Turner, J.C. Reynolds
The rapid screening of volatile organic compounds (VOCs) by direct analysis has potential applications in the areas of food and flavour science. Currently, the technique of choice for VOC analysis is gas chromatography/mass spectrometry (GC/MS). However, the long chromatographic run times and elaborate sample preparation associated with this technique have led a movement towards direct analysis techniques, such as selected ion flow tube mass spectrometry (SIFT-MS), proton transfer reaction mass spectrometry (PTR-MS) and electronic noses. The work presented here describes the design and construction of a Venturi jet-pump-based modification for a compact mass spectrometer which enables the direct introduction of volatiles for qualitative and quantitative analysis.
The MS analysis was carried out using Advion Expression® CMS with vAPCI.
Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP®) without exposure to the air presents a problem.
Here, the inert ASAP probe (iASAP), a modification of the technique developed by Professor Ingo Krossing’s group at the Albert-Ludwigs-University of Freiburg, allows sampling and transportation in an environment of inert gas to prevent decomposition of the compound.
Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP ®) without exposure to the air presents a problem. Here, the inert ASAP probe (iASAP), a modification of the technique developed by Professor Ingo Krossing’s group at the Albert-Ludwigs-University of Freiburg, allows sampling and transportation in an environment of inert gas to prevent decomposition of the compound.