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Application: Lipidomics

Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signaling

Zech, T.; Ejsing, C.S.; Gaus, K.; de Wet, B.; Shevchenko, A.; Simons, K.; Harder, T.
EMBO J. 2009, 28: 466–476.

High-throughput analysis of gangliosides in defined regions of fetal brain by fully automated chip-based nanoelectrospray ionization multi-stage mass spectrometry

Serb, A.; Schiopu, C.; Flangea, C.; Vukelić, Z.; Sisu, E.; Zagrean, L.; Zamfir, A. D.
Eur J Mass Spectrom. 2009;15(4):541-53.

Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput platform for shotgun lipidomics

Han, X.; Yang, K.; Gross, R.W. Rapid Commun Mass Spectrom. 2008 Jul;22(13):2115-24

Coupling of fully automated chip-based electrospray ionization to high-capacity ion trap mass spectrometer for ganglioside analysis

Almeida, R.; Mosoarca, C.; Chirita, M.; Udrescu ,V.; Dinca, N.; Vukelic, Z.; Allen, M.; Zamfir, A.D.
Anal Biochem. 2008 Jul 1;378(1):43-52. [Epub 2008 Mar 28]

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

Matyash, V.; Liebisch, G.; Kurzchalia, T.V.; Shevchenko, A.; Schwudke D.;
J. Lipid Res. 2008, 49: 1137-1146

Shotgun Lipidomics Identifies a Paired Rule for the Presence of Isomeric Ether Phospholipid Molecular Species

Yang, K.; Zhao, Z.; Gross, R. W.; Han, X.
PLoS ONE. 2007 ; 2(12): e1368

Automated Identification and Quantification of Glycerophospholipid Molecular Species by Multiple Precursor Ion Scanning

Ejsing, C.S.; Duchoslav E.; Sampaio, J.; Simons, K.; Bonner, R.; Thiele, C.; Ekroos, K.; Shevchenko, A.
Anal. Chem. 2006 , 78(17):6202-14

Osmolality, temperature and membrane lipid composition modulate the activity of betaine transporter BetP in Corynebacterium glutamicum

Özcan, N.; Ejsing, C.S.; Shevchenko, A.; Lipski, A.; Morbach, S.; Krämer, R.
J. Bacteriol. 2007 , 189(20): 7485-7496

Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry

Murphy, R.C.; James, P.F.; McAnoy, A.M.; Krank, J.; Duchoslav, E.; Barkley, R.M.
Anal. BioChem. 2007 , 366:59-70

Top-Down Lipidomic Screens by Multivariate Analysis of High-Resolution Survey Mass Spectra

Schwudke, D.; Hannich, J.T.; Surendranath, V.; Grimard, V.; Moehring, T.; Burton , L.; Kurzchalia, T.; Shevchenko, A. Anal. Chem. 2007, Published on web.

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