Integration with Agilent Technologies’ (U)HPLC Liquid Chromatography Systems

The expression CMS was designed by expert mass spectroscopists and chemists to create the ideal platform for scientists to get the most out of their research. Full integration (control, data acquisition, and analysis) with Agilent Technologies’ LC systems allows users a streamlined approach for their LC/CMS methods.

Ion Chromatography Determination of Inorganic Anions Coupled With the Advion Compact Mass Spectrometer (CMS)

There is a concerted effort by regulatory bodies, such as the EPA to reduce the exposure of environmental contaminants, such as inorganic anions to humans and the environment.

Achieving lower analytical detection limits of hazardous compounds in environmental matrices such as water, soils and sediments allows regulatory bodies to make better informed decisions on the degree of contamination of an environmental system as well as the remedial actions required to limit adverse health and environmental effects.

Mass spectrometry provides the tool to achieve lower detection limits and greater selectivity when compared to conductivity and UV detectors.

Mass spectrometry guided purification for efficient isolation of natural products at semi- and preparative scale

In natural product research the isolation of compounds from crude extracts is a key element. An increase in the efficiency of the purification process, by improvement of instrumental and methodological approaches, remains a crucial point. In this respect, modern flash chromatography, has evolved and uses 15 μm spherical particles for efficient separation at moderate pressures. Flash C-18 was tested for the rapid isolation of various plant secondary metabolites of interest.

Positive Ion APCI LC/MS Analysis of Enlite Herbicides

There must be better ways to do sample preparation for food matrices! And with good sample prep better analyses occur. It is human nature to resist change. Let us embrace new ways of doing things if they can be shown to be better, faster and easier.

Real-Time monitoring of a Suzuki reaction utilizing a hood-based compact mass spectrometer

A novel compact single quadrupole mass spectrometer for hood-based applications in the analysis of chemical reactions.

Medical chemists are routinely faced with personally over a hundred new chemical entities (NCE’s) each year for testing as future pharmaceutical drug candidates. The goal is to prepare a high yield, relatively pure product via an optimized synthetic route.