US Patent Granted for Key Element of the NanoTek Microfluidic Synthesis System

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ITHACA, NY, USA, February 5, 2010 — Advion BioSystems, Inc. (Advion) announced the issuance of U.S. patent No. 7641860 for their reconfigurable multistage microreactor cartridge apparatus, a key module of the Advion NanoTek Microfluidic Synthesis System (NanoTek), which is primarily used by leading Positron Emission Tomography (PET) radiochemists around the world.

PET, which uses specific biomarkers labeled with small amounts of radioactivity, is a powerful technique used in both clinical diagnostic medicine and in advanced medical research and pharmaceutical development. The core technology of the NanoTek system, microfluidic flow chemistry, has proven to be an attractive alternative to conventional vial-based chemistry for radiochemical labeling. The advantages include reduced reaction times and higher radiochemical yields. Researchers who have utilized the NanoTek system in their labs report the ability to conduct multiple sequential syntheses from one delivery of radioisotope, greatly accelerating the optimization of new compounds.

Andy Holley, NanoTek Product Manager, states, “This component enables our users to rapidly reconfigure the NanoTek system for different syntheses. We are pleased that this innovative technology has been recognized and is now protected by the granting of this patent.”

Jack Henion, Co-founder and Chief Scientific Officer of Advion added, “Advion is proud of our track record in innovative research. The granting of this patent is yet one more confirmation of our leadership in microfluidic technology.”

About Advion BioSystems, Inc.
Advion is the scientific leader in microfluidic systems. The company’s scientific knowledge base creates unique nanotechnologies delivering speed, flexibility, and exceptional data quality. Advion is the microfluidics supplier of choice for customers demanding scientific excellence, more information from complex samples, and greater throughput. More about the company can be found at

For Advion:
Heather Scollins
Sr. Marketing Communication Specialist
Advion BioSciences, Inc.
p: 1.607.266.0665 ext. 333