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Advion Interchim Scientific Announces Appointment of Jamey Jones, to Chief Executive Officer

Advion Interchim Scientific Announces Appointment of Jamey Jones, to Chief Executive Officer

ITHACA, N.Y., USA, / MONTLUÇON, FRANCE, December 07, 2023 — Advion Interchim Scientific, renowned for its expertise in mass spectrometry and chromatography instruments and consumables, announced today that Jamey Jones will immediately become Chief Executive Officer of the Advion Interchim Scientific group.

The appointment encompasses the chief leadership role at both Advion Inc. and Adchim (Interchim group), two companies operating under the Advion Interchim Scientific brand. Officially, Mr. Jones is the CEO of Advion Inc., and the Directeur Général of Adchim/Interchim SAS.

Mr. Jones has led the Advion Inc. team for over 15 consecutive years, serving as the Senior Vice President of Operations and Technology, and most recently, President and Chief Operating Officer at Advion Inc. and Interchim SAS. Prior to his tenure at Advion, he spent over 15 years in technical and leadership roles at Biotage AB, Northrop Grumman, and serving in the United States Navy.

“For over a decade, I have worked with my colleagues at Advion Interchim Scientific, embracing strategic thinking and scientific management, driving product development, and promoting positive change in the scientific industry. It is my honor to take on the role of CEO for AIS. Together, we embark on a journey of continued growth, innovation, and shared success. I am grateful for the trust placed in me and am committed to steering our companies towards new horizons. With a relentless focus on collaboration and excellence, I am confident our collective efforts will elevate us to unprecedented achievements. The future is bright, and I am honored to lead us into this next chapter.

Advion Interchim Scientific has a number of legal entities and sells its life science solutions via direct sales support operations in North America, UK, Europe, Japan, India, and China.  And more than 100 distributors provide Advion Interchim Scientific solutions globally.

About Advion Interchim Scientific:
At Advion Interchim Scientific, we deliver tailored solutions to improve our customers’ most challenging identification, quantification, and purification needs with our broad range of innovative instruments, consumables, reagents, and scientific expertise.

Our unrivaled portfolio ranges from media and columns to consumables, accessories, and instruments for flash chromatography, preparative (U)HPLC, analytical (U)HPLC, mass spectrometry, ICP-MS, coupled with intelligent apps and software.

Strategically aligned for global growth, we recognize that our success has always come from our customers, and we are dedicated and committed to providing best-in-class service and support worldwide.

For Advion Interchim Scientific

Kristy Licari
Sr. Director of Marketing
Telephone: 1-607-882-9903
Email: kristy.licari@advion-interchim.com

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Advion Interchim Scientific Receives ISO 9001:2015 Certification

Advion Interchim Scientific Receives ISO 9001:2015 Certification

ITHACA, N.Y., USA, November 9, 2023 — Advion Interchim Scientific, renowned for its expertise in mass spectrometry and chromatography instruments and consumables, proudly announces its ISO 9001:2015 certification for its Advion division. This milestone underscores the company’s dedication to superior scientific instrumentation, consumables, and customer service excellence.

The ISO 9001:2015 is globally recognized as the benchmark for quality management systems (QMS), signifying rigorous adherence to customer and regulatory mandates. Certified organizations demonstrate a robust customer focus, streamlined processes, and an unwavering commitment to continuous improvement. Advion’s achievement of this certification is a clear indicator of its relentless drive for quality in every facet of its business.

The attainment of the ISO 9001:2015 certification cements Advion Interchim Scientific’s promise to deliver top-tier quality within the life sciences sector. It provides its customers, partners, and stakeholders with the assurance of the company’s compliance with stringent international quality standards.

Dr. Kaveh Kahen, CEO of Advion Inc., states, “Our foremost goal at Advion Interchim Scientific is to not only meet but surpass customer expectations. The ISO 9001:2015 certification of our Advion division is a powerful endorsement of our steadfast dedication. Moreover, it highlights the robustness of our internal systems as we strive for operational excellence, process quality, and ongoing enhancement.”

Committed to upholding its ISO 9001:2015 certification, Advion Interchim Scientific pledges to continuously refine its quality management practices to guarantee unparalleled quality, dependability, and customer contentment.

About Advion Interchim Scientific:
At Advion Interchim Scientific, we deliver tailored solutions to improve our customers’ most challenging identification, quantification, and purification needs with our broad range of innovative instruments, consumables, reagents, and scientific expertise.

Our unrivaled portfolio ranges from media and columns to consumables, accessories, and instruments for flash chromatography, preparative (U)HPLC, analytical (U)HPLC, mass spectrometry, ICP-MS, coupled with intelligent apps and software.

Strategically aligned for global growth, we recognize that our success has always come from our customers, and we are dedicated and committed to providing best-in-class service and support worldwide.

For Advion Interchim Scientific

Kristy Licari
Sr. Director of Marketing
Telephone: 1-607-882-9903
Email: kristy.licari@advion-interchim.com

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Helium Shortages in the Chemistry Lab: Compound Characterization Using Helium-Free Techniques

Helium shortages are not new – annually, scientists see the cost of helium rise and fall like the stock market. Except this isn’t just a financial impact. Global helium shortages threaten to derail research and essential industry functions, taking down GC and high-field NMR instruments, bringing a once state-of-the-art lab down to a bare-bones facility.

This whitepaper explores the use of alternative reaction monitoring technology, including the expression® CMS (Compact Mass Spectrometer), Plate ExpressTM TLC Plate Reader, and ASAP® probe for liquid and solid samples – all helium-free alternatives for the chemistry laboratory.

Reaction Monitoring Capabilities at the Bench:

The expression® CMS offers an ideal reaction monitoring solution that will live on long beyond the helium shortage and become a centerpiece of the lab. The system offers a complete solution for: 

  • Batch and flow chemistry 
  • Fast compound identification and purity determination
  • …with little or no sample preparation required, and many novel sample introduction interfaces

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Mistletoe: Kiss of Love or Death? Using Thin Layer Chromatography with Compact Mass Spectrometry

Mistletoe

Mass Spec: expression® CMS
Sampling: Plate Express™ 

 In the spirit of the Holiday season and to ensure that mistletoe kisses are enjoyed and are ‘non-toxic’, we employed the Advion Interchim Scientific expression® Compact Mass Spectrometer (CMS) and the Plate Express™ TLC Plate Reader to analyze a commercial Tincture of Mistletoe ethanolic extract to determine whether tyramine is present in the extract of mistletoe. 

INTRODUCTION 

A sprig of mistletoe symbolizes a tradition of romance (Figure 1), and has a legacy of folklore purporting that extracts of mistletoe can cure cancer along with a long list of other reported health benefits. However, mistletoe is also considered lethal. Reputed to be the “kiss of death”, mistletoe is said by some to be so poisonous that humans can be killed if they ingest the leaves or berries. 

Figure 1: The tradition of mistletoe.
Mistletoe

The reported toxicity made us wonder, why or how can vendors sell mistletoe extracts for purposeful human consumption? One species of mistletoe, Viscum, reportedly contains the poisonous alkaloid, tyramine, which can cause blurred vision, nausea, abdominal pain, diarrhea, blood pressure changes, and even death. A search of peer-reviewed scientific literature reveals a dearth of credible analytical support for the presence of tyramine in mistletoe. 

In the spirit of the Holiday season and to ensure that mistletoe kisses are enjoyed and are ‘non-toxic’, we employed the Advion Interchim Scientific TLC/CMS system (Figure 2) to analyze a commercial tincture of Mistletoe ethanolic extract to determine whether tyramine is present in the extract of mistletoe.

Figure 2: Experimental setup of the Advion Interchim Scientific expression® CMS with the Plate Express™ TLC Plate Reader.
CMS and Plate Express
Figure 3: Experimental herbs used.
Mistletoe herb

EXPERIMENTAL 

A tincture of mistletoe was purchased from Indigo Herbs. A small aliquot of this tincture sample was derivatized with dansyl chloride at 50 ºC for 30 min according to well-known procedures[1]. Similarly, an authentic sample of tyramine was derivatized in the same manner to form its dansyl derivative. 

A small aliquot (10 mL) of the standard tyramine dansyl derivative was applied to the outside lanes (Lanes 1 and 4) of a Merck Silica gel G TLC plate. An aliquot of the derivatized tincture of mistletoe was applied to Lane 2 and a derivatized tincture of mistletoe spiked with tyramine dansyl derivative was applied to Lane 3 (Figure 4). 

Figure 4: TLC plate after development and visualization under long wavelength UV light. Lanes 1 and 4: Dansyl derivative of standard tyramine. Lane 2: Dansyl derivative reaction mixture of mistletoe tincture sample. Lane 3: Tincture extract dansyl derivative with standard tyramine dansyl derivative spiked into it. (A) Rf=0.3 for tyramine dansyl derivative. (B) Rf=0.6 for dansyl chloride.
Mistletoe Results

The air-dried TLC plate was developed in an equilibrated solvent tank containing chloroform/ethyl (8/2, v/v) acetate. The developed TLC plate was then viewed under long wavelength UV light to reveal the separated components (Figure 3). The TLC plate was positioned onto the Plate Express™ TLC Plate Reader whereupon each TLC ‘spot’ could be individually analyzed by TLC/CMS. 

With reference to Figure 4, the TLC/CMS analysis readily showed that the Rf 0.3 spots in the two outside lanes (Lanes 1 and 4) produced a mass spectrum with an abundant m/z 371 consistent with the expected protonated molecule of the tyramine dansyl derivative (Figure 5A). The TLC/CMS mass spectra obtained from the spots with an Rf=0.6 observed in Lanes 1 and 4 were consistent with unreacted dansyl chloride with a protonated molecule at m/z 270 (data not shown). TLC/CMS analysis of the spot in lane 2 at Rf=0.3 showed no evidence for the presence of tyramine dansyl derivative (Figure 5B). 

Figure 5: (A) TLC/CMS mass spectrum of standard tyramine dansyl derivative observed at Rf=0.3 in Figure 4 Lane 1. (B) LC/CMS mass spectrum of derivatized tincture of mistletoe observed at Rf=0.3 in Figure 4 Lane 2. 

Mistletoe Spectra

In the absence of TLC/CMS analysis, it would be logical to conclude the spot at Rf=0.3 in lane 2 was due to the presence of tyramine in the mistletoe tincture sample. The Rf=0.3 spot observed for the fortified tincture extract in Lane 3 of Figure 4 readily showed the same mass spectrum for tyramine dansyl derivative that is shown in Figure 5A. The same negative results for tyramine were obtained from the alcohol extract of the mistletoe leaf product. 

CONCLUSIONS 

The results from this brief study suggest either that the level of tyramine in the tincture sample is very low and below our detection limits or that tyramine is not present in the sample. It is common for synthetic and forensic chemists to employ TLC techniques as a quick, easy screen of a sample to determine the presence of an expected chemical. Comparison with a known sample, which shows the same Rf value, will often provide some confidence for reporting the presence of the expected compound. However, as this example suggests a similar Rf value does not guarantee confirmation of the spot identity when it has the same Rf value. As shown here, access to the direct analysis of the spot with the Advion Interchim Scientific expression® CMS can either corroborate the expected identification or, as in this case, suggest that the spot with the same Rf value is NOT the expected compound. These results may explain why the commercial mistletoe tincture samples are not harmful for medicinal purposes. So, what should you do? Mistletoe is not deadly. But it can be hazardous, so don’t eat it. Just ‘steal a kiss under it’! 

REFERENCES AND ACKNOWLEDGEMENT 

[1]Mullins, Donald E. and Eaton, John L. Quantitative high-performance thin-layer chromatography of dansyl derivatives of biogenic amines, Anal. Biochem., 1988, 172, (484-487). 

Thank you to Chief Elf, Nigel Sousou, Ph.D., for leading the sample analysis process. 

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Advion Interchim Scientific Expands Global Footprint with New Offices in Japan, India

ITHACA, N.Y., December 9, 2021 — Advion Interchim Scientific, the market-facing name of a partnership between Advion, Inc. and Interchim SAS, announces two new global centers in Japan and India. To meet market demand, the two new subsidiaries will support instrument and consumable sales and service in these rapidly growing regions, bringing a wide range of flash chromatography, mass spectrometry, and consumables solutions.

“We have the opportunity to work with several of the industry’s brightest minds to create a global channel for the Advion Interchim Scientific line of consumables, accessories, and instruments for flash chromatography, preparative (U)HPLC, analytical (U)HPLC, mass spectrometry, and ICP-MS,” said Dr. Kaveh Kahen, CEO of Advion Interchim Scientific. “With incredible innovation and rapid growth in the Indian and Japanese markets, now is an ideal time to establish subsidiaries in these markets to offer our world-class instrumentation and services.”

In India, Inkarp Instruments PVT LTD., a long-time strategic partner and distributor of Advion Inc, is leading the joint venture “Advion Interchim Scientific Pvt Ltd.,” to create a dynamic offering for the scientific industry combining abundant knowledge and fine reputation of the established Inkarp team paired with the Advion Interchim Scientific range of advanced instrumentation in flash, prep, mass spectrometry and more.

“Inkarp Instruments and Advion Inc. have been partners in India since 2013, and we are delighted to announce our joint venture, Advion Interchim Scientific Pvt Ltd.,” said Natesh Krishnamurthy, CEO of Inkarp, India. “Our goal of bringing world-class chromatography and spectroscopy opportunities to one of the fastest-growing global economies is a strategic move that capitalizes on the Advion Interchim Scientific mission to provide industry-leading identification, quantification, and purification tools on a global scale. With the complete portfolio of products, we will now be able to address a larger market and build on our success with the Advion Interchim Scientific’s Compact Mass Spectrometry systems in India. This joint venture reinforces the strong relationship built over many years of cooperation between our companies.”

In Japan, a direct subsidiary was formed and will provide a dedicated pipeline of instrumentation and consumables to the pharmaceutical and academic segments.

“I look forward to contributing to the growing industry demands in Japan” said Mr. Koji Yokota, General Manager of Advion Interchim Scientific, Japan. “The innovation in Japan is moving at a rapid pace – a pace which the Advion Interchim Scientific suite of systems and consumables will undoubtedly be ready to support.”

For inquiries in Japan, please contact Mr. Koji Yokota, Koji.Yokota@advion-interchim.com. For India, please contact Mr. Vijay Gupta, Vijay.gupta@advion-interchim.com. For all other global inquiries, please contact info@advion-interchim.com.

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About Advion Interchim Scientific:
At Advion Interchim Scientific, we deliver tailored solutions to improve our customers’ most challenging identification, quantification, and purification needs with our broad range of innovative instruments, consumables, reagents, and scientific expertise.

Our unrivaled portfolio ranges from media and columns to consumables, accessories, and instruments for flash chromatography, preparative (U)HPLC, analytical (U)HPLC, mass spectrometry, ICP-MS, coupled with intelligent apps and software.

Strategically aligned for global growth, we recognize that our success has always come from our customers, and we are dedicated and committed to providing best-in-class service and support worldwide.

About Inkarp Instruments:
Inkarp Instruments is one of the top distribution companies in India. It is headquartered in Hyderabad and has regional office covering most regions of India. Inkarp Instruments is continuing to mark its prominence and presence in the analytical instrument market for world class instrument supply, installation and services. Since 1985 the organization has been catering to a very wide range of customers for their requirements of analytical instruments.

For Advion Interchim Scientific:

Kristy Licari
Sr. Director of Marketing
Advion Interchim Scientific
Telephone: 1-607-882-9903
Email: kristy.licari@advion-interchim.com

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Advion Interchim Scientific Offers New SOLATION® ICP-MS with Superior Performance, Exceptional Value

Advion Interchim Scientific Offers New SOLATION® ICP-MS with Superior Performance, Exceptional Value

ITHACA, N.Y., November 2, 2021 — Advion Interchim Scientific, the market-facing name of a partnership between Advion, Inc. and Interchim SAS, announces the release of the new SOLATION® Inductively Coupled Plasma Mass Spectrometer (ICP-MS), featuring market competitive performance specifications paired with user-friendly software. The SOLATION® ICP-MS fills a significant gap, where customer demand for robust performance and simplicity meets a lower price point.

The SOLATION® ICP-MS offers high performance, multi-elemental analysis, ideal for environmental, clinical, biomedical, food, agriculture, and geological applications. Sensitive to consumer needs, the system is thoughtfully designed for lower argon consumption and is accompanied with an innovative 90° quadrupole deflector for lower interference and improved signal-to-noise ratio.

“Our team at Advion Interchim Scientific has developed a robust, easy-to-use ICP-MS system that truly facilitates heavy metal analysis workflow in routine applications,” said Dr. Kaveh Kahen, Advion Interchim Scientific CEO. “Academic, food, agricultural and cannabis labs will find the SOLATION® ICP-MS offers strong performance, has an intuitive software for optimization and data analysis, and is a perfect fit for routine elemental analysis. Paired with best-in-class service and support, any organization in need of high-quality elemental analysis assays will find their ideal match with the SOLATION® ICP-MS.”

In addition to the SOLATION®, Advion Interchim Scientific manufacturers a wide range of tools for the chemist, including the puriFlash® family of flash purification systems, the expression® Compact Mass Spectrometer, the AVANT® (U)HPLC, and many other novel sample introduction systems including the Plate Express® TLC Plate reader and the TriVersa NanoMate® nano-electrospray ionization technique.

The SOLATION® ICP-MS is available now. Visit www.advion.com/products/SOLATION-ICP-MS for more details and product specifications.

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About Advion Interchim Scientific:
At Advion Interchim Scientific, we deliver tailored solutions to improve our customers’ most challenging identification, quantification, and purification needs with our broad range of innovative instruments, consumables, reagents, and scientific expertise.

Our unrivaled portfolio ranges from media and columns to consumables, accessories, and instruments for flash chromatography, preparative (U)HPLC, analytical (U)HPLC, mass spectrometry, ICP-MS, coupled with intelligent apps and software.

Strategically aligned for global growth, we recognize that our success has always come from our customers, and we are dedicated and committed to providing best-in-class service and support worldwide.

For Advion Interchim Scientific:
Kristy Licari, Sr. Director of Marketing • Advion Interchim Scientific
Telephone: 1-607-882-9903 • Email: kristy.licari@advion-interchim.com

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Advion announces appointment of Dr. Kaveh Kahen as new CEO, David B. Patteson remains as group Chairman

ITHACA, N.Y., November 19, 2020 — Advion, Inc. announces that Dr. Kaveh KavehKahenKahen will immediately become CEO of the Advion group.  David Patteson, the prior Chairman and CEO of the group will remain as group Chairman. Dr. Kahen will be closely involved in the proposed combination of Advion and Interchim, presently underway and as previously announced, and would assume a resulting executive leadership position.

“Dr. Kahen’s background and success is a perfect fit for our global group of companies.  He is an acknowledged world expert in the fields of ICP-MS, LC-MS, GC-MS, and Cannabis analysis.” remarked Patteson.

Dr. Kahen was a former R&D and Business executive at AB SCIEX and PerkinElmer, and more recently the Chairman and CEO of Sigma Analytical Services, Canada’s premier medical cannabis testing and consulting company. Mr. Kahen led PerkinElmer’s mass spectrometry business unit for several years and was responsible for the introduction of new LC-MS/MS and ICP-MS platforms and the company’s successful entry into the Chinese mass spectrometry market.

“I am honored and excited to have been selected to lead the Advion Group. With Advion’s strong and established brand in drug discovery, biopharma, and academia and our company’s leadership in flash and prep LC, I see tremendous opportunities to build scale and synergy and strategically target several high growth markets with our fit-for-purpose solutions.”

Advion has a number of legal entities and sells its life science solutions via direct sales support operations in North America, Europe and China.  More than 100 distributors provide Advion solutions in other global regions.

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About Advion, Inc.

Advion’s nearly three-decade dedication to serving scientists yields customer-focused life science solutions. Our deep scientific, engineering and customer workflow knowledge spawns an unrivaled solution portfolio.  We work directly with, train, and passionately advocate for our customers to ensure their success. Dedicated to Science – Dedicated to You. More about Advion, Inc. can be found on our website, www.advion.com.

For Advion, Inc.

Kristy Licari
Director of Marketing
Advion, Inc.
Telephone: 1-607-882-9903
Email: klicari@advion.com