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Application: Clinical

Controlled Protein Precipitation in Combination with Chip-Based Nanospray Infusion Mass Spectrometry. An Approach for Metabolomics Profiling of Plasma

Boernsen, K.O.; Gatzek, S.; Imbert, G.;
Anal. Chem. 2005; 77(22):7255-64

The combination of liquid chromatography/tandem mass spectrometry and chip-based infusion for improved screening and characterization of drug metabolites

Staack, R.F.; Varesio, E.; Hopfgartner, G.
Rapid Commun. Mass Spectrom. 2005; 19:618–626

Identification of a novel glutathione adduct of diclofenac, 4′-hydroxy-2′-glutathion-deschloro-diclofenac, upon incubation with human liver microsomes

Yu, L. J.; Chen, Y.; Deninno, M. P.; O’Connell, T. N.; Hop, C. E.
Drug Metab Dispos. 2005 Apr.;33(4):484-8. [Epub 2005 Jan 7]

Off-line capillary electrophoresis/fully automated nanoelectrospray chip quadrupole time-of-flight mass spectrometry and tandem mass spectrometry for glycoconjugate analysis

Bindila, L.; Almeida, R.; Sterling, A.; Allen, M.; Peter-Katalinic, J.; Zamfir, A.
J. Mass Spectrom. 2004;39:1190–1201

Fully-automated chip-based nanoelectrospray tandem mass spectrometry of gangliosides from human cerebellum;

Zamfir, A.; Vukelic, Z.; Bindila, L.; Peter-Katalinic, J.; Almeida, R.; Sterling, A.; Allen, M.;
J. Am. Soc. Mass. Spectrom. 2004;15(11):1649-57

Quantitation of midazolam in human plasma by automated chip-based infusion nanoelectrospray tandem mass spectrometry

Kapron, J.T.; Pace, E.; Van Pelt, C.K.; Henion, J.
Rapid Commun Mass Spectrom. 2003;17(18):2019-26

Electrospray ionization mass spectrometry-based genotyping: an approach for identification of single nucleotide polymorphisms

Zhang, S.; Van Pelt, C.K.; Schultz, G.A.
Anal Chem. 2001 May 1;73(9):2117-25

A fully integrated monolithic microchip electrospray device for mass spectrometry

Schultz, G.A.; Corso, T.N.; Prosser, S.J.; Zhang, S.
Anal Chem. 2000 Sep 1;72(17):4058-63

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