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Application: Metabolite Identification

Automated liquid microjunction surface sampling-HPLC-MS/MS analysis of drugs and metabolites in whole-body thin tissue section

V. Kertesz; G.J. Van Berkel Bioanalysis 2013 Apr;5(7):819-26. doi: 10.4155/bio.13.42.

Investigation of figopitant and its metabolites in rat tissue by combining whole body autoradiography with liquid extraction surface analysis mass spectrometry

Schadt, S.; Kallback, S.; Almeida, R.; Sandel, J.
Drug Metab Dispos. [Epub 2011 Dec 19]. doi:10.1124/dmd.111.043562

Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

Eikel, D.; Vavrek, M.; Smith, S.; Bason, C.; Yeh, S.; Korfmacher, W. A.; Henion, J. D.
Rapid Commun Mass Spectrom. 2011 Dec 15;25(23):3587-3596. [Epub 2011 Nov 16]

Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism

Blatherwick, E.Q.; Van Berkel, G.J.; Pickup, K.; Johansson, M.K.; Beaudoin, M.E.; Cole, R.O.; Day, J.M.; Iverson, S.; Wilson, I.D.; Scrivens, J.H., Weston, D.J.
Xenobiotica. 2011 Aug;41(8):720-34. [Epub 2011 Jun 14]

High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas

Giavalisco, P.; Hummel, J.; Lisec, J.; Inostroza, A.C.; Catchpole, G.; Willmitzer, L. Anal Chem. 2008 Dec 15;80(24):9417-25

Rapid metabolite identification with sub parts-per-million mass accuracy from biological matrices by direct infusion nanoelectrospray ionization after clean-up on a ZipTip and LTQ/Orbitrap mass spectrometry

Erve, J.C.; Demaio, W.; Talaat, R.E.
Rapid Commun Mass Spectrom. 2008 Oct;22(19):3015-26

Comparison of a two-dimensional liquid chromatography/mass spectrometry approach with a chip-based nanoelectrospray device for structural elucidation of metabolites in a human ADME study using a quadrupole time-of-flight mass spectrometer

Trunzer, M.; Graf, D.; Kiffe, M.
Rapid Commun. Mass Spectrom. 2007; 21(6):937-44

Mechanism for the elimination of aromatic molecules from polyenes in tandem mass spectrometry

Guaratini, T.; Lopes, N.P.; Pinto, E.; Colepicolo, P.; Gates, P.J.
Chem. Commun. (Camb). 2006 Oct. 21;389(5):1439-46 [Epub ahead of print]

Quantitation of cotinine in nonsmoker saliva using chip-based nanoelectrospray tandem mass spectrometry

Tomkins, B.A.; Van Berkel, G.J.; Jenkins, R.A.; Counts, R.W.
J Anal Toxicol. 2006 Apr;30(3):178-86

Letter: Radical ion and protonated molecule formation with retinal in electrospray and nanospray

Guaratini, T.; Gates, P.J.; Cardozo, K.H.; Campos , P.M.; Colepicolo, P.; Lopes, N.P.
Eur. J. Mass Spectrom. ( Chichester , Eng. ). 2006;12(1):71-4

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