Analytical Sciences Synthesis & Purification: Consumables, Reagents & Instruments

The new edition of our “Analytical Sciences, Synthesis & Purification” catalog is available now! Offering a full suite of innovative products and technologies from Advion Interchim Scientific, this catalog features over 20,000 products ranging from consumables and reagents to instrumentation.

Not only a product resource, the catalog features in-depth scientific information to improve your daily workflow, including sample preparation tips and tricks, analysis technologies such as GC and LC/MS, and help selecting the best consumables for your workflow or purification.

Take advantage of this extensive guide to boost your lab with:

  • 20,000 Products
  • 12 Chapters
  • Technicals Tips
  • New Systems

Synthesis and full characterization of an iridium B–H activation intermediate of the monocarba-closo-dodecaborate anion

The preparation and full characterization of an iridium complex of the monocarba-closo-dodecaborate anion is reported. It was prepared by B–H bond activation using a tosyl amide directing group.

Analysis by spectroscopic methods and X-ray crystallography revealed the presence a direct B–Ir interaction. The carborane acts as aB,N chelating ligand towards the Ir(Cp*)(solvent) fragment, resulting in a monomeric complex that is inert in solution and the solid state.

Treatment with N-chlorosuccinimide resulted in selective monochlorination of the B–Ir position. In addition, its structure, spectroscopic features and reactivity were investigated by DFT calculations.

The Role of Mass Spectrometry in the Drug Discovery Unit’s Workflow – Medicinal Chemistry & the Advion CMS

The Drug Discovery Unit at the University of Dundee is met daily with a global task: address unmet medical needs and diseases in the developing world, and continuously build their innovative targets portfolio.

Learn from Susan Davis, a Medicinal Chemist with the unit, how she has processed 22,639 sample injections via the Advion compact mass spectrometer, and how it has assisted her research daily.

Also hear from Dr. Jack Henion, Advion’s Scientific Founder, as he joins for a Q&A session about mass spec and it’s role in drug discovery and disease prevention. 

This webinar examines the workflow of a medicinal chemist as they utilize compact mass spectrometry techniques for drug discovery and disease prevention.

expression® CMS: Mass Spectrometers Designed for Chemists

With decades of mass spectrometry and chemistry expertise, Advion Interchim Scientific has produced a family of compact mass spectrometers designed for the chemist. The affordability, small size and ease of use make them ideal for use directly at the chemist’s bench, giving immediate answers and informed decisions instead of waiting.

The Advion Interchim Scientific expression® compact mass spectrometer (CMS) is a fast and easy analytical tool for the organic chemist. Ideal for fast reaction monitoring, the expression® CMS features a single quadrupole that can adapt to multiple ionization sources in seconds, including both ESI and APCI. The mass spectrometer works in a variety of applications, including food and beverage, pharmaceutical, biomedical, peptides and proteins, drug discovery and more. The expression® CMS offers a variety of novel sampling techniques, including:

  • Direct mass analysis of TLC plates in 30 seconds at the push of a button with Plate Express
  • One-touch analysis of solids and liquid samples with the ASAP® probe
  • LC/CMS
  • Many more options and configurations to suit your needs

Learn more about the different sample techniques available with the expression® CMS, including fast assay methods for liquids, solids, gases, and even air-sensitive compounds.

Fill out the form to download the full expression® CMS brochure now.

Ion Chromatography Determination of Inorganic Anions Coupled With the Advion Compact Mass Spectrometer (CMS)

There is a concerted effort by regulatory bodies, such as the EPA to reduce the exposure of environmental contaminants, such as inorganic anions to humans and the environment.

Achieving lower analytical detection limits of hazardous compounds in environmental matrices such as water, soils and sediments allows regulatory bodies to make better informed decisions on the degree of contamination of an environmental system as well as the remedial actions required to limit adverse health and environmental effects.

Mass spectrometry provides the tool to achieve lower detection limits and greater selectivity when compared to conductivity and UV detectors.