Integrated Solutions for Food Authenticity, Characterization and Safety with the expression® Compact Mass Spectrometer, AVANT® (U)HPLC and SOLATION® ICP-MS
Your integrated laboratory solution for comprehensive testing of food, ingredients and natural products. Advion offers a full suite of analytical instrumentation for characterization, screening and purity determination, including:
expression® CMS – The expression® Compact Mass Spectrometer (CMS) offers the industry’s widest range of sample introduction systems, providing rapid answers with little or no sample prep in < 30 seconds.
SOLATION® ICP-MS – Provides fast, simple, multi-element analysis of toxic metals, and essential elements and minerals in a wide array of samples, including water, soil, plant material, food and raw ingredients
AVANT® HPLC & UHPLC – Advion’s range of modular high performance, liquid chromatography systems can be used standalone with UV and UV/Vis detector options, or with the expression® CMS to provide seamlessly integrated LC/CMS under the full control of Advion’s simple, intuitive software suite.
PLATE EXPRESS® TLC PLATE READER – Plate Express® provides a simple, automated means of obtaining mass spectra directly from TLC plates, combined with Advion’s expression® CMS creating a technique known as TLC/ CMS. See results in < 30 seconds at the push of a button.
Integrated Solutions for Potency and Safety with the expression® Compact Mass Spectrometer and SOLATION® ICP-MS
Outfit your lab with Advion Interchim Scientific’s line of custom cannabis solutions, including the expression® Compact Mass Spectrometer (CMS), the SOLATION® ICP-MS, and a customizable (U)HPLC solution.
Your Complete Lab Solution: Advion Interchim Scientific provides integrated laboratory solutions for comprehensive cannabis testing, including potency testing and cannabinoid levels as well as pesticide identification and quantitation of heavy metals.
P. Perez-Hurtado, E. Palmer, T. Owen, C. Aldcroft, M.H. Allen, J. Jones,,C.S. Creaser, M.R. Lindley, M.A. Turner, J.C. Reynolds
The rapid screening of volatile organic compounds (VOCs) by direct analysis has potential applications in the areas of food and flavour science. Currently, the technique of choice for VOC analysis is gas chromatography/mass spectrometry (GC/MS). However, the long chromatographic run times and elaborate sample preparation associated with this technique have led a movement towards direct analysis techniques, such as selected ion flow tube mass spectrometry (SIFT-MS), proton transfer reaction mass spectrometry (PTR-MS) and electronic noses. The work presented here describes the design and construction of a Venturi jet-pump-based modification for a compact mass spectrometer which enables the direct introduction of volatiles for qualitative and quantitative analysis.
The MS analysis was carried out using Advion Expression® CMS with vAPCI.
Bacteria can be benign, beneficial and harmful, for more than 70 years we have been combatting these microscopic creatures with antibiotics. Increasingly though strains of antimicrobial resistant bacteria are becoming commonplace. This has motivated numerous studies aimed at deciphering the evolution of antibiotic resistance. Volatile Organic Compounds (VOCs) are ubiquitous in nature and are produced through various metabolic and catabolic processes. The profile of bacterial VOCs could therefore offer an insight into the detection of the type of bacteria and how they grow. This research utilizes a Volatile Atmospheric Pressure Chemical Ionization (vAPCI) source coupled to a Advion CMS instrument for detection of bacterial VOCs from in-vitro samples. This rapid and non-invasive approach of sampling VOCs and the implementation of a metabolomics workflow discriminates between E.coli and staphylococcus aureus and demonstrates how bacterial profiles can change over time.
TLC/CMS, the atmospheric liquids and solids probe (ASAP), and the volatile APCI source provide direct analysis without sample preparation – even for air-sensitive compounds.
With the daily need to analyze a variety of samples, these techniques are indispensable in a busy lab.
Learn how a single instrument can be adapted to each of these sample requirements and rapidly changed to accommodate back-to-back assays. Listen to users in the field speak about the innovative sample inlets that have cut down on sample prep and streamlined their everyday work flow.
During this webinar you will:
Learn how the CMS offers real-time results and decision making right at the bench. This allows chemists to optimize reactions, know when to quench, and know when they have failed and to move on
Learn several novel sample techniques that can streamline workflow in your lab
Find fast analysis methods for liquids, solids and vapor-phase compounds
Hear from leaders in mass spectrometry including:
Dr. Jack Henion, Advion Scientific Founder
Matthew Turner, Experimental Officer in Mass Spectrometry, Department of Chemistry, Loughborough University
Tao Yongfeng, Post Doctorate, The Romo Group, Baylor University
Sean M. Kerwin, PhD, Associate Professor, Department of Chemistry & Biochemistry, Texas State University
Aim: Breath analyses have potential to detect early signs of disease onset. Ambient ionization allows direct combination of breath gases with MS for fast, on-line analysis. Portable MS systems would facilitate field/clinic-based breath analyses.
Results & methodology: Volunteers ingested peppermint oil capsules and exhaled volatile compounds were monitored over 10 h using a compact mass spectrometer. A rise and fall in exhaled menthone was observed, peaking at 60–120 min. Real-time analysis showed a gradual rise in exhaled menthone postingestion. Sensitivity was comparable to established methods, with detection in the parts per trillion range.
Conclusion: Breath volatiles were readily analyzed on a portable mass spectrometer through a simple inlet modification. Induced changes in exhaled profiles were detectable with high sensitivity and measurable in real-time.
Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. The video demonstrates analysis of a reaction mixture.
Quant Express, an addition to Advion’s user-friendly Mass Express 4.0 software suite, features quantitation to create a fully integrated software system for expression CMS users.
At regular intervals throughout the year a local lawn service applies pesticides to the lawn surrounding the Advion headquarters in Ithaca, NY. The grass is very uniform and not a single dandelion or crabgrass plant is visible – so we wondered, what chemical do they use? After an application in the early spring, we sampled the yellow pellets and utilized the Advion expression® CMS (compact mass spectrometer) coupled with a vapor Atmospheric Pressure Chemical Ionization (vAPCI) ion source to determine the unknown chemical.