Category: Blog

The ability to effectively screen passengers with minimal personal contact is critical. Ion mobility detectors used at many airports can be inaccurate and provide many false-positives and false-negatives. Advanced Imaging Technology (AIT) screening techniques are very useful for detecting concealed weapons and explosive devices located on passengers and/or in their belongings, however are unable to detect trace amounts of explosive residues.

Direct sample analysis is possible via an Atmospheric Solids Analysis Probe (ASAP®) combined with atmospheric pressure chemical ionization (APCI) on a compact mass spectrometer (CMS). This technique allows for the rapid investigation (<30 sec) of material suspected of containing THC/cannabinoids.

Reinaldo Almeida, Zane Berzina, Eva C. Arnspang, Jan Baumgart, Johannes Vogt, Robert Nitsch, and Christer S. Ejsing

Here we describe a novel surface sampling technique termed pressurized liquid extraction surface analysis (PLESA), which in combination with a dedicated high resolution shotgun lipidomics routine enables both quantification and in-depth structural characterization of molecular lipid species extracted directly from tissue sections.

Chemists are tasked with quickly identifying compounds created, ensuring quality of products or evaluating safety. Current techniques are adequate, but not all offer speed, data quality or ease-of-use provided by the expression Compact Mass Spectrometer (CMS). The expression CMS with the direct analysis probe (ASAP®) offers chemists the ability to rapidly analyze solids, liquids and powders without tedious and time consuming sample preparation.

Surface analysis techniques have gained significant attention over the last couple of years with LESA being an interesting alternative to techniques such as SIMS or MALDI imaging. A new application note demonstrates practical applications for LESA in the material sciences.

See examples for the determination of amino acids on a combined HPLC compact mass spectrometry (LC/CMS) system for the rapid detection and quantification of amino acids utilizing a novel mixed mode LC column.

Associate Professor Christer S. Ejsing at the University of Southern Denmark uses the TriVersa NanoMate, as an essential laboratory instrument, for the development and applications of Lipidomic technology.

Researchers in the UK have demonstrated the use of Liquid Extraction Surface Analysis (LESA) on the TriVersa NanoMate for top-down identification of proteins directly from living bacterial colonies grown in Petri dishes, without sample preparation. The method offers “improved sampling precision and could be useful for spatial profiling of bacterial colonies or analysis of contaminated surfaces.”

Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. Our new video demonstrates analysis of a reaction mixture.

The expression Compact Mass Spectrometer (CMS) provides lower detection limits and greater selectivity for Perchlorate compared to a conductivity detector (CD).