Cloth swipes are a fairly common sampling modality, having relevance across a wide variety of applications including environmental analysis, forensics, and bioassays. One of the biggest attractions of swipes (and related paper substrates) is the ease of sample collection and transportation, where just the swipe of a surface is required to collect particulates or solution phase species, with the substrate then readily transported to laboratory facilities. Additionally, the possibility to sample low-volume analytes, such as blood, gunshot residue, etc., provides additional benefits. The modes for the analytical sampling of the immobilized material vary greatly based on the means of analysis. These vary from direct solid analysis by a variety of optical probing methods, to solvent rinsing/extraction, and complete ashing/digestion of the cloth to liberate adsorbed species. Of the methods applied for elemental (metals) analysis of swipe materials, inductively coupled plasma-mass spectrometry (ICP-MS) is the most versatile in terms of coverage and sensitivity. Recently, a direct microextraction approach has been described for uranium isotope ratio determinations. Here, we describe the initial methodology development towards the use of the Advion Interchim Scientific® Plate Express™ microextraction device, coupled to an Advion Interchim Scientific® SOLATION® ICP-MS, for simultaneous, multielement analysis. Practical means of identifying test sites and evaluating elution quality are described. Methods of multielement quantification are identified with preliminary figures of merit presented. Finally, use of the method to quantify metals spiked into a synthetic urine matrix is demonstrated. While areas of improvement are clearly suggested, this rapid (<2 min) method of direct microextraction into the ICP (Ex-ICP-MS) shows great promise for use across diverse applications.
Advion Interchim Scientific® SOLATION® ICP-MS and Plate Express™ (Advion, Ithaca, NY) was utilized.
In this application note, we demonstrate a complete solution for the synthesis, purification, and quantitation of Gd(III)-DOTA, an ionic imaging contrast agent with better chemical stability and lower toxicity compared to the currently used Gd-(DTPA).
In this application note, we present a fast method for routine analysis of small volume blood samples for key toxic and essential elements using the Advion Interchim Scientific® SOLATION® Inductively Coupled Plasma Mass Spectrometer (ICP-MS) using a simple “dilute and shoot” sample preparation.
Recorded February 2, 2023: LIVE Location, the 2023 European Winter Conference on Plasma Spectrochemistry
Janez Ilaš, Ph. D., Professor, University of Ljubljana
Fadi Abou-Shakra, Director of Advion Interchim Scientific® ICP-MS Portfolio
Join Advion Interchim Scientific® with guest speaker from the University of Ljubljana, Faculty of Pharmacy, to learn more about a new novel sample introduction method for ICP-MS utilizing direct analysis via microextraction. First you will learn microextraction methods with the Plate Express TLC Plate/microextraction reader coupled to the single-quadrupole expression® Compact Mass Spectrometer (CMS). After understanding the basics of the platform, you will learn more about how this technology was reimagined to suit the SOLATION® ICP-MS for a rapid method to determine isotopic analysis faster and easier than ever before.
Maximize your analytical spectroscopy workflow in pharmaceutical applications—even with limited space at the bench. This session features innovative solutions for streamlining everyday needs in the lab, including reaction monitoring utilizing fast, prep-free sample introduction techniques for answers in seconds. You will also learn the latest technology in heavy metal analysis, as well as purification tools to maximize your scale-up efforts.
As a viewer, you will learn more about:
How to obtain direct mass analysis from TLC plates in seconds
Prep-free mass sampling techniques such as a direct analysis probe
How heavy metal analysis technology has improved for maximum use in the pharmaceutical lab
How scale-up needs can be met with the latest purification technologies
In this application note we present a method for routine analysis of 21 elements using the Advion Interchim Scientific® SOLATION® Inductively Coupled Plasma Mass Spectrometer (ICP-MS). A group of unknown soil samples and a CRM were digested using EPA 3051a and analyzed according to method 6020a requirements.
Recorded November 3, 2022: Featured talk in the LCGC Mass Spectrometry Symposium
Join Fadi Abou-Shakra, Director of ICP-MS Portfolio for Advion Interchim Scientific®, as he shares some of the organization’s latest mass spectrometry applications for the teaching lab. This includes student-friendly experiments using a compact single-quadrupole system, as well as simplified ICP-MS applications.
Fadi Abou-shakra started using ICP-MS in 1987 applying it for the analysis of trace elements in biological fluids and has been active in the field of atomic spectroscopy since then. He holds an MSc in Medical Physics and a PhD in Chemistry from the University of Surrey, England. He brings a wealth of experience in ICP-MS as a researcher, customer support specialist and a business manager.
Lab Manager Ask the Expert Webinar. Recorded September 15, 2022
Out of your element? Don’t be! This webinar features innovative cannabis and blood applications, plus tips and tricks to maximize throughput, precision, and sensitivity when utilizing ICP-MS technology. Performed using the Advion Interchim Scientific SOLATION® ICP-MS featuring a state-of-the-art sample introduction from Glass Expansion, this session is a must-see for any user or future user seeking tools for heavy metal analysis.
As a viewer, you will learn more about:
How to perform heavy metal analysis of cannabis plants using the SOLATION® ICP-MS
Simple methods for blood and plasma analysis that any lab can perform
How spray chamber performance can affect long-term system stability
Webinar speakers include:
Dr. Fadi Abou-Shakra Director of ICP-MS Portfolio Advion Interchim Scientific
ICP-MS Application Scientist Advion Interchim Scientific
Cannabis and hemp products are becoming much more available for medicinal and recreational use making routine testing for toxic heavy metals much more important. Advion Interchim Scientific® introduces the SOLATION® ICP-MS for the analysis of heavy metals in cannabis plant and cannabis product samples. While there are no federal guidelines for heavy metals in cannabis, states where cannabis use and production are legal have adopted exposure limits and QC criteria for Arsenic, Cadmium, Mercury, and Lead based on USP<233>. Here, we report the results of our sample analysis using these guidelines.
This poster was presented at the 2021 ASMS conference in Philadelphia, PA, USA.
Environmental monitoring is vital to understanding the world around us. Air quality, water, and soil testing all provide valuable information about an environment’s status. Tools and technologies for environmental monitoring can be used to evaluate the sanitation of a food and beverage lab or to monitor an ecosystem’s recovery after an oil spill. Join Lab Manager and our panel of experts as we review the tools available for environmental testing and monitoring.
As an attendee, you will learn more about:
Developments in technology for environmental testing and monitoring
Considerations when purchasing technology for environmental testing and monitoring
Applications for environmental testing and monitoring across industries
This webinar was hosted by Lab Manager Tech Trends and recorded July 9, 2020.