Resource Center

A book of experiments for your students The expression® CMS (Compact Mass Spectrometer) is the ideal instrument for the teaching lab thanks to its small size, ease of use, and one-click software. This pocket guide of classroom experiments offers students the ability to gain hands-on instrument experience by eliminating complex and difficult sample preparation.

Maximize your analytical spectroscopy workflow in pharmaceutical applications—even with limited space at the bench. This session features innovative solutions for streamlining everyday needs in the lab, including reaction monitoring utilizing fast, prep-free sample introduction techniques for answers in seconds. You will also learn the latest technology in heavy metal analysis, as well as purification tools …

In this application note, a method to separate and purify 3 curcuminoids from turmeric powder using thin layer chromatography (TLC) with mass spectrometry and flash chromatography is demonstrated.

Recorded November 3, 2022: Featured talk in the LCGC Mass Spectrometry Symposium Join Fadi Abou-Shakra, Director of ICP-MS Portfolio for Advion Interchim Scientific®, as he shares some of the organization’s latest mass spectrometry applications for the teaching lab. This includes student-friendly experiments using a compact single-quadrupole system, as well as simplified ICP-MS applications. Fadi Abou-shakra started …

The new edition of our “Analytical Sciences, Synthesis & Purification” catalog is available now! Offering a full suite of innovative products and technologies from Advion Interchim Scientific, this catalog features over 20,000 products ranging from consumables and reagents to instrumentation. Not only a product resource, the catalog features in-depth scientific information to improve your daily …

Avoid workflow bottlenecks by streamlining the flash purification process in your lab. This whitepaper can help you identify, reduce, or even eliminate these bottlenecks, tanking your standard operational time from hours to minutes. Learn how essential tools including TLC, a smartphone application and a simple dipping probe for fraction ID offer a novel, systematic approach …

This webinar features several useful tools to simplify or even eliminate the sample preparation involved prior to mass spectrometry. In this educational session you will learn about several prep-free mass spec techniques that are available, and how to select which method is best for your analysis. Advion will share their perspectives on some of the …

Authors: Max Planck Institute for Polymer Research, Germany; University of Twente, Netherlands Abstract We developed a simple way to create 2D conductive nanostructures with dielectric cores and conductive surfaces based on polyethylene with in-chain thiophene groups. Generally, thiophene-based polymers show great conductive properties, but exhibit a poor processability. Here, we use the crystallization of a …

Successfully completing an organic synthesis involves three typically lengthy, but crucial steps: reaction monitoring, compound identification, and purification. These steps can create bottlenecks in the synthesis, unless a purpose-built, streamlined, and reliable workflow is on hand. This whitepaper delves into some of the challenges faced by synthetic organic chemists as they navigate compound identification and …

The compound synthesis, purification and confirmation processes often present challenges. From ensuring successful synthesis of your product, setting up a flash purification method, and finally confirming ID of fractions, the lengthy work flow can be time consuming and repetitive. This webinar will provide a foundation for flash purification processes, and will showcase a novel work …

Mass spectrometry is an analytical technique used to determine the mass-to-charge ratio of ions in a sample and therefore the sample composition. This method is used across many industries including food and beverage, environmental monitoring, and clinical. There are many features of mass spectrometers that must be considered before purchasing such as the required mass …

Environmental monitoring is vital to understanding the world around us. Air quality, water, and soil testing all provide valuable information about an environment’s status. Tools and technologies for environmental monitoring can be used to evaluate the sanitation of a food and beverage lab or to monitor an ecosystem’s recovery after an oil spill. Join Lab …

Lab Manager Tech Trends Webinar. Recorded June 25, 2020. Food and beverage labs use techniques from other disciplines such as microbiology, environmental monitoring, and analytical chemistry to test for food and beverage contaminants. Unlike these disciplines, the food and beverage industry is highly regulated and therefore food and beverage labs have very specific needs. Join …

A simple, sensitive and selective ASAP® sample introduction approach to measuring the presence of two isobaric compounds, CBDA and THCA, contained in a complex sample such as hemp or cannabis plants or their corresponding extraction products. Measurements are made of differences in the relative composition of CBDA and THCA fragment ions originating from the same …

The combination of the Advion Interchim Scientific expression® CMS and puriFlash® flash chromatography technologies speed up the synthesis, purification and characterization of a compound. Using the Advion Interchim Scientific expression® Compact Mass Spectrometer, the Plate Express™ TLC Plate reader, the ASAP® Atmospheric Solids Analysis Probe, and the puriFlash® XS520 flash purification system, it is now possible to execute …

The compound synthesis, purification and confirmation process often presents challenges throughout. From ensuring successful synthesis of your product, setting up a flash purification method, and finally confirming ID of fractions, the lengthy work flow can be time consuming and repetitive. In this application note, we demonstrate how the combination of Advion and Interchim technologies speed …

The combination of the Advion Interchim Scientific® expression® CMS puriFlash® flash chromatography technologies speed up the synthesis, purification and characterization of a compound. Watched the video and ready to learn more? View More TLC to Flash Details

The Advion Interchim Scientific suite of systems and consumables allows users to harness the power of mass spectrometry, flash chromatography, prep LC and more. Simple and robust, download our brochure to learn more about: The Advion Interchim Scientific expression® compact mass spectrometer (CMS): A fast and easy analytical tool for the organic chemist. Ideal for fast …

The recent outbreak of severe lung injury is allegedly tied to the presence of Vitamin E Acetate (VEA) in vaping-related products after VEA was found in lung fluid samples of patients with vaping-related lung illness (EVALI). Calling for regulatory control, Washington, Colorado and Ohio have already banned the use of VEA in e-juices at the state …

In this Lab Manager webinar, Dr. Daniel Eikel, Advion Director of Product Applications and Customer Service reviews the use of the Advion expression Compact Mass Spectrometer (CMS) for food and beverage analysis. As an attendee, you will learn more about: How leading technologies and techniques affect food science researchers How to establish workflows that optimize …

This webinar examines three different workflows surrounding compact mass spectrometry as they apply to cannabis law enforcement, it’s natural product research, and product control.

In this webinar, Advion’s Scientific Founder, Jack Henion, Ph.D., will discuss his research using a direct analysis probe coupled with the expression CMS to analyze chemical compounds in Cannabis. During this webinar you will learn more about: A simple, sensitive and selective ASAP sample introduction approach to measure the presence and relative quantitative composition of …

Thanks to the diminishing size and cost of mass spectrometers, coupled with their increasing robustness and ease of use, universities are now starting to furnish their undergraduate chemistry laboratories with this advanced analytic tool. “My favorite learning environment is the laboratory,” explains Paul A. Flowers, professor of analytical chemistry at University of North Carolina at …

The expression® CMS provides essential information quickly and improves the chemist’s workflow by using a direct analysis probe, otherwise known as ASAP® (Atmospheric Solids Analysis Probe) permits chemists affordable and reliable sample analysis of solid and liquid samples such as reaction mixtures, food samples, natural products and tablets. Chemists simply dip the closed end of …

Advion’s direct atmospheric solids analysis probe, otherwise known as ASAP^®, permits chemists fast and reliable sample analysis of liquid and solid samples such as reaction mixtures, food samples, natural products and tablets.

Advion’s expression® CMS paired with the Atmospheric Solids Analysis Probe (ASAP®) can quickly and easily be used to screen an unidentified drug mixture in this mobile field testing dramatization.

Reaction monitoring is a key aspect in a range of chemistry environments from chemical synthesis to drug discovery to understanding natural products to protein synthesis. Understanding the optimal time to quench a reaction for maximum yield, as well as monitoring a reaction in real-time is vital to many medicinal and synthetic organic chemists. Advion Interchim …

In this webinar, Heather Walker from Sheffield University’s plant production and protection team explains how taking a compact mass spectrometer from the lab to the field helped optimise the team’s research. The webinar highlights the advantages of mobile mass spectrometry, and introduces a mobile mass spec vehicle that has been outfitted to optimize time in the …

Bring mass spectrometry into your classroom for remote or on-site learning with a training course for the expression® Compact Mass Spectrometer (CMS). Advion offers an affordable MS teaching package that includes: A compact, easy-to-use benchtop mass spectrometer for both students and researchers Recorded lectures and video lab content Lecture slides to share or adapt to your own teaching style …

Integrated Solutions for Food Authenticity, Characterization and Safety with the expression® Compact Mass Spectrometer, AVANT® (U)HPLC and SOLATION® ICP-MS  Your integrated laboratory solution for comprehensive testing of food, ingredients and natural products. Advion offers a full suite of analytical instrumentation for characterization, screening and purity determination, including: expression® CMS – The expression® Compact Mass Spectrometer (CMS) offers …

Integrated Solutions for Potency and Safety with the expression® Compact Mass Spectrometer and SOLATION® ICP-MS Outfit your lab with Advion Interchim Scientific’s line of custom cannabis solutions, including the expression® Compact Mass Spectrometer (CMS), the SOLATION® ICP-MS, and a customizable (U)HPLC solution. Your Complete Lab Solution: Advion Interchim Scientific provides integrated laboratory solutions for comprehensive cannabis …

For Direct Mass Analysis of Liquid & Solid Samples with the expression® CMS The direct atmospheric solids analysis probe, otherwise known as ASAP®, permits chemists fast and reliable sample analysis of liquid and solid samples such as reaction mixtures, food samples, natural products and tablets. Chemists simply dip the closed end of a glass capillary …

Overview A simple, sensitive and selective ASAP® sample introduction approach to measuring the presence of two isobaric compounds, CBDA and THCA, contained in a complex sample such as hemp or cannabis plants or their corresponding extraction products. Measurements are made of differences in the relative composition of CBDA and THCA fragment ions originating from the …

Maria Baskin, Natalia Fridman, Monica Kosa, Galia Maayan We describe the construction of synthetically challenging heteroleptic complexes by capitalizing on the solubility properties of their corresponding favored homoleptic complexes. We demonstrate that the formation of a heteroleptic Cu2+ complex based on 2,2′:6′,2′′-terpyridine (Terpy) and 8-hydroxyquinoline (HQ) is not possible due to the insolubility of (HQ)2Cu2+. …

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to quickly identify the presence of artificial vanilla, as well as confirm the purity of products marketed as such. This technique provides a fast and easy method for purity analysis.

Overview: Direct sample analysis is possible via an Atmospheric Solids Analysis Probe (ASAP®) combined with atmospheric pressure chemical ionization (APCI) on a compact mass spectrometer. This technique allows for the rapid investigation (<30 sec) of material suspected of containing trace amounts of explosive residues. The expression® Compact Mass Spectrometer (CMS) with an Atmospheric Solids Analysis …

The expression® CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

TLC/CMS, the atmospheric liquids and solids probe (ASAP), and the volatile APCI source provide direct analysis without sample preparation – even for air-sensitive compounds. With the daily need to analyze a variety of samples, these techniques are indispensable in a busy lab. Learn how a single instrument can be adapted to each of these sample …

Quant Express, an addition to Advion’s user-friendly Mass Express 4.0 software suite, features quantitation to create a fully integrated software system for expression CMS users.

In this application note, we demonstrate the use of the Advion expressionL CMS with an atmospheric solids analysis probe (ASAP) ion source to analyze two supplements (figure 1) that contain DMBA, a synthetic stimulant that has not been tested on humans. The substance is the chemical cousin to drug DBAA, which is currently banned by …

The CheMS user interface simplifies the mass spectrometry experience and makes it more accessible in chemistry and biochemistry laboratories. This allows the chemist to obtain optimal data without needing to be an expert in mass spectrometry. Available with the Advion expression® compact mass spectrometer (CMS) is a fast and easy tool that is ideal for …

An office colleague has stolen a prized chocolate bar, and Dr. Eikel with the help of his partner, Dr. Henion, use an Atmospheric Solids Analysis Probe (ASAP) enabled expression CMS to determine whodunnit. This application note describes the process, and points the finger at the guilty culprit!

Advion has the cover story of the September 2015 issue of the Journal of Mass Spectrometry. We present a method requiring no sample preparation for the direct identification of indigoid colorants in tiny amounts in ancient historic fabrics using ASAP®-MS. Exact determinations were completed in less than 1 min.

Spectroscopyonline.com Jul 01, 2015 By Daniel Eikel, Simon J. Prosser, Jack D. Henion Special Issues Issue 7, pg 20–27 The transition of cannabis from an illegal drug to a drug for medical and even recreational use raises challenging questions for regulatory agencies and analytical chemists alike. Here, we show a selection of analytical techniques based …

The scientific investigation of cultural heritage objects is the only access to knowledge about long-gone, ancient societies and their cultural, technological as well as their social  stage of development. In addition, the materials used by our ancestors, e.g. their textiles and the organic dyestuff to colorize these materials, allow researchers to draw some conclusions about …

With decades of mass spectrometry and chemistry expertise, Advion Interchim Scientific has produced a family of compact mass spectrometers designed for the chemist. The affordability, small size and ease of use make them ideal for use directly at the chemist’s bench, giving immediate answers and informed decisions instead of waiting. The Advion Interchim Scientific expression® compact …

The ability to effectively screen passengers with minimal personal contact is critical. Ion mobility detectors used at many airports can be inaccurate and provide many false-positives and false-negatives. Advanced Imaging Technology (AIT) screening techniques are very useful for detecting concealed weapons and explosive devices located on passengers and/or in their belongings, however are unable to …

Direct sample analysis is possible via an Atmospheric Solids Analysis Probe (ASAP®) combined with atmospheric pressure chemical ionization (APCI) on a compact mass spectrometer (CMS). This technique allows for the rapid investigation (<30 sec) of material suspected of containing THC/cannabinoids.

The expression CMS with the direct analysis probe offers chemists the ability to rapidly analyze solids, liquids and powders without tedious and time consuming sample preparation.

Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. The video demonstrates analysis of a reaction mixture.

The expression CMS provides essential compound information quickly and improves the chemist’s workflow. The Atmospheric Solids Analysis Probe (ASAP®) permits fast analysis of solid and liquid samples and is a simple, low cost alternative to LC/MS methods. This direct analysis probe method has been shown to be useful for the analysis of volatile and semivolatile …

The expression CMS provides essential compound information quickly and improves the chemist’s workflow. The Atmospheric Solids Analysis Probe (ASAP®) permits fast analysis of solid and liquid samples and is a simple, faster and lower cost alternative to LC/MS methods. This direct analysis probe method has been shown to be useful for the analysis of volatile …

The expression CMS was developed with the chemist’s objectives and laboratory workflow in mind. Organic, Natural Product and Peptide chemists utilize many techniques to determine the progress, yield and purity of their reactions.